Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion

AIMS: Neutrophil extracellular trap formation (NETosis) increases atherosclerotic plaque vulnerability and athero-thrombosis. However, mechanisms promoting NETosis during atherogenesis are poorly understood. We have shown that cholesterol accumulation due to myeloid cell deficiency of the cholestero...

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Detalles Bibliográficos
Autores principales: Yalcinkaya, Mustafa, Fotakis, Panagiotis, Liu, Wenli, Endo-Umeda, Kaori, Dou, Huijuan, Abramowicz, Sandra, Xiao, Tong, Libby, Peter, Wang, Nan, Tall, Alan R, Westerterp, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153645/
https://www.ncbi.nlm.nih.gov/pubmed/36537208
http://dx.doi.org/10.1093/cvr/cvac189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153645/
https://www.ncbi.nlm.nih.gov/pubmed/36537208
http://dx.doi.org/10.1093/cvr/cvac189

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