Toward a pan-SARS-CoV-2 vaccine targeting conserved epitopes on spike and non-spike proteins for potent, broad and durable immune responses

BACKGROUND: The SARS-CoV-2 non-Spike (S) structural protein targets on nucleocapsid (N), membrane (M) and envelope (E), critical in the host cell interferon response and memory T-cell immunity, are grossly overlooked in COVID vaccine development. The current Spike-only vaccines bear an intrinsic sho...

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Detalles Bibliográficos
Autores principales: Wang, Chang Yi, Peng, Wen-Jiun, Kuo, Be-Sheng, Ho, Yu-Hsin, Wang, Min-Sheng, Yang, Ya-Ting, Chang, Po-Yen, Shen, Yea-Huei, Hwang, Kao-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153712/
https://www.ncbi.nlm.nih.gov/pubmed/37079651
http://dx.doi.org/10.1371/journal.ppat.1010870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153712/
https://www.ncbi.nlm.nih.gov/pubmed/37079651
http://dx.doi.org/10.1371/journal.ppat.1010870

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