Repurposing antifungals: population pharmacokinetics of itraconazole and hydroxy-itraconazole following administration of a nanocrystal formulation

OBJECTIVES: To describe itraconazole and hydroxy-itraconazole pharmacokinetics following intravenous (IV) administration of a previously developed nanocrystal formulation (NCF) in haematopoietic cell transplant (HCT) recipients for prophylaxis of invasive fungal disease. METHODS: In a prospective Ph...

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Detalles Bibliográficos
Autores principales: Jansen, Anouk M E, Ter Heine, Rob, Donnelly, J P, Blijlevens, Nicole, Brüggemann, Roger J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154123/
https://www.ncbi.nlm.nih.gov/pubmed/36935381
http://dx.doi.org/10.1093/jac/dkad072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154123/
https://www.ncbi.nlm.nih.gov/pubmed/36935381
http://dx.doi.org/10.1093/jac/dkad072

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