Cargando…

Microglial activation protects against accumulation of tau aggregates in nondemented individuals with underlying Alzheimer’s disease pathology

The role of microglia in tau accumulation is currently unclear but could provide an important insight into the mechanisms underlying Alzheimer’s disease (AD)(1). Here, we measured the microglial marker soluble TREM2 and the disease-associated microglial activation stage 2 markers AXL, MERTK, GAS6, L...

Descripción completa

Detalles Bibliográficos
Autores principales: Pereira, Joana B., Janelidze, Shorena, Strandberg, Olof, Whelan, Christopher D., Zetterberg, Henrik, Blennow, Kaj, Palmqvist, Sebastian, Stomrud, Erik, Mattsson-Carlgren, Niklas, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154192/
https://www.ncbi.nlm.nih.gov/pubmed/37118533
http://dx.doi.org/10.1038/s43587-022-00310-z