LncRNA XIST regulates breast cancer stem cells by activating proinflammatory IL-6/STAT3 signaling

Aberrant expression of XIST, a long noncoding RNA (lncRNA) initiating X chromosome inactivation (XCI) in early embryogenesis, is a common feature of breast cancer (BC). However, the roles of post-XCI XIST in breast carcinogenesis remain elusive. Here we identify XIST as a key regulator of breast can...

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Detalles Bibliográficos
Autores principales: Ma, Yuxi, Zhu, Yongyou, Shang, Li, Qiu, Yan, Shen, Na, Wang, Jonathan, Adam, Tiffany, Wei, Wei, Song, Qingxuan, Li, Jun, Wicha, Max S., Luo, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154203/
https://www.ncbi.nlm.nih.gov/pubmed/36922677
http://dx.doi.org/10.1038/s41388-023-02652-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154203/
https://www.ncbi.nlm.nih.gov/pubmed/36922677
http://dx.doi.org/10.1038/s41388-023-02652-3

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