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Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
The licensed drug rapamycin has potential to be repurposed for geroprotection. A key challenge is to avoid adverse side effects from continuous dosing. Here we show that geroprotective effects of chronic rapamycin treatment can be obtained with a brief pulse of the drug in early adulthood in female...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154223/ https://www.ncbi.nlm.nih.gov/pubmed/37118497 http://dx.doi.org/10.1038/s43587-022-00278-w |