CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease

Cerebrospinal fluid (CSF) amyloid-β peptide (Aβ)42/Aβ40 and the concentration of tau phosphorylated at site 181 (p-tau181) are well-established biomarkers of Alzheimer’s disease (AD). The present study used mass spectrometry to measure concentrations of nine phosphorylated and five nonphosphorylated...

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Detalles Bibliográficos
Autores principales: Barthélemy, Nicolas R., Saef, Benjamin, Li, Yan, Gordon, Brian A., He, Yingxin, Horie, Kanta, Stomrud, Erik, Salvadó, Gemma, Janelidze, Shorena, Sato, Chihiro, Ovod, Vitaliy, Henson, Rachel L., Fagan, Anne M., Benzinger, Tammie L. S., Xiong, Chengjie, Morris, John C., Hansson, Oskar, Bateman, Randall J., Schindler, Suzanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154225/
https://www.ncbi.nlm.nih.gov/pubmed/37117788
http://dx.doi.org/10.1038/s43587-023-00380-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154225/
https://www.ncbi.nlm.nih.gov/pubmed/37117788
http://dx.doi.org/10.1038/s43587-023-00380-7

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