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Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase

C-linked glycosylation is essential for the trafficking, folding and function of secretory and transmembrane proteins involved in cellular communication processes. The tryptophan C-mannosyltransferase (CMT) enzymes that install the modification attach a mannose to the first tryptophan of WxxW/C sequ...

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Detalles Bibliográficos
Autores principales: Bloch, Joël S., John, Alan, Mao, Runyu, Mukherjee, Somnath, Boilevin, Jérémy, Irobalieva, Rossitza N., Darbre, Tamis, Scott, Nichollas E., Reymond, Jean-Louis, Kossiakoff, Anthony A., Goddard-Borger, Ethan D., Locher, Kaspar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154233/
https://www.ncbi.nlm.nih.gov/pubmed/36604564
http://dx.doi.org/10.1038/s41589-022-01219-9