Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC)

TNFα is a key mediator of immune, chemotherapy and radiotherapy-induced cytotoxicity, but several cancers, including head and neck squamous cell carcinomas (HNSCC), display resistance to TNFα due to activation of the canonical NFκB pro-survival pathway. However, direct targeting of this pathway is a...

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Detalles Bibliográficos
Autores principales: Morgan, Ethan L., Toni, Tiffany, Viswanathan, Ramya, Robbins, Yvette, Yang, Xinping, Cheng, Hui, Gunti, Sreenivasulu, Huynh, Angel, Sowers, Anastasia L., Mitchell, James B., Allen, Clint T., Chen, Zhong, Van Waes, Carter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154301/
https://www.ncbi.nlm.nih.gov/pubmed/37055579
http://dx.doi.org/10.1038/s41418-023-01144-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154301/
https://www.ncbi.nlm.nih.gov/pubmed/37055579
http://dx.doi.org/10.1038/s41418-023-01144-x

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