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Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC)
TNFα is a key mediator of immune, chemotherapy and radiotherapy-induced cytotoxicity, but several cancers, including head and neck squamous cell carcinomas (HNSCC), display resistance to TNFα due to activation of the canonical NFκB pro-survival pathway. However, direct targeting of this pathway is a...
Autores principales: | Morgan, Ethan L., Toni, Tiffany, Viswanathan, Ramya, Robbins, Yvette, Yang, Xinping, Cheng, Hui, Gunti, Sreenivasulu, Huynh, Angel, Sowers, Anastasia L., Mitchell, James B., Allen, Clint T., Chen, Zhong, Van Waes, Carter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154301/ https://www.ncbi.nlm.nih.gov/pubmed/37055579 http://dx.doi.org/10.1038/s41418-023-01144-x |
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