Extending the use of biologics to mucous membranes by attachment of a binding domain

Biologics are almost exclusively administered systemically, but localized delivery is preferable as it minimizes off-target exposure and allows more aggressive treatments. Topical application of biologics to epithelia is generally ineffective because most are covered with fluids and biologics are wa...

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Detalles Bibliográficos
Autores principales: Shanks, Robert M. Q., Romanowski, Eric G., Romanowski, John E., Davoli, Katherine, McNamara, Nancy A., Klarlund, Jes K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154311/
https://www.ncbi.nlm.nih.gov/pubmed/37130912
http://dx.doi.org/10.1038/s42003-023-04801-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154311/
https://www.ncbi.nlm.nih.gov/pubmed/37130912
http://dx.doi.org/10.1038/s42003-023-04801-6

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