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Lineage tracing of mutant granulosa cells reveals in vivo protective mechanisms that prevent granulosa cell tumorigenesis

Ovarian granulosa cell tumors (GCTs) originate from granulosa cells (GCs) and represent the most common sex cord-stromal tumor in humans. However, the developmental regulations and molecular mechanisms underlying their etiology are largely unknown. In the current study, we combined a multi-fluoresce...

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Detalles Bibliográficos
Autores principales: Niu, Shudong, Cheng, Kaixin, Jia, Longzhong, Liang, Jing, Mu, Lu, Wang, Yibo, Yang, Xuebing, Yang, Chen, Zhang, Yan, Wang, Chao, Huang, Lijun, Wang, Huarong, Zhang, Shuang, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154338/
https://www.ncbi.nlm.nih.gov/pubmed/36823373
http://dx.doi.org/10.1038/s41418-023-01132-1