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Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation

Dendritic spines are the postsynaptic sites for most excitatory glutamatergic synapses. We previously demonstrated a severe spine loss and synaptic reorganization in human neocortices presenting Type II focal cortical dysplasia (FCD), a developmental malformation and frequent cause of drug‐resistant...

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Detalles Bibliográficos
Autores principales: Rossini, Laura, De Santis, Dalia, Cecchini, Erica, Cagnoli, Cinzia, Maderna, Emanuela, Cartelli, Daniele, Morgan, Bryan Paul, Torvell, Megan, Spreafico, Roberto, di Giacomo, Roberta, Tassi, Laura, de Curtis, Marco, Garbelli, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154370/
https://www.ncbi.nlm.nih.gov/pubmed/36564349
http://dx.doi.org/10.1111/bpa.13141