CHCHD2 p.Thr61Ile knock‐in mice exhibit motor defects and neuropathological features of Parkinson's disease

The p.Thr61Ile (p.T61I) mutation in coiled‐coil‐helix–coiled‐coil‐helix domain containing 2 (CHCHD2) was deemed a causative factor in Parkinson's disease (PD). However, the pathomechanism of the CHCHD2 p.T61I mutation in PD remains unclear. Few existing mouse models of CHCHD2‐related PD complet...

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Detalles Bibliográficos
Autores principales: Fan, Liyuan, Zhang, Shuo, Li, Xinwei, Hu, Zhengwei, Yang, Jing, Zhang, Shuyu, Zheng, Huimin, Su, Yun, Luo, Haiyang, Liu, Xinjing, Fan, Yu, Sun, Huifang, Zhang, Zhongxian, Miao, Jinxin, Song, Bo, Xia, Zongping, Shi, Changhe, Mao, Chengyuan, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154378/
https://www.ncbi.nlm.nih.gov/pubmed/36322611
http://dx.doi.org/10.1111/bpa.13124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154378/
https://www.ncbi.nlm.nih.gov/pubmed/36322611
http://dx.doi.org/10.1111/bpa.13124

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