Cargando…

Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2

Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal form of pancreatic cancer, characterised by stromal remodelling, elevated matrix stiffness and high metastatic rate. Retinoids, compounds derived from vitamin A, have a history of clinical use in cancer for their anti-proliferativ...

Descripción completa

Detalles Bibliográficos
Autores principales: Matellan, Carlos, Lachowski, Dariusz, Cortes, Ernesto, Chiam, Kai Ning, Krstic, Aleksandar, Thorpe, Stephen D., del Río Hernández, Armando E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154384/
https://www.ncbi.nlm.nih.gov/pubmed/37130839
http://dx.doi.org/10.1038/s41389-023-00467-1