Cargando…
Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2
Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal form of pancreatic cancer, characterised by stromal remodelling, elevated matrix stiffness and high metastatic rate. Retinoids, compounds derived from vitamin A, have a history of clinical use in cancer for their anti-proliferativ...
Autores principales: | Matellan, Carlos, Lachowski, Dariusz, Cortes, Ernesto, Chiam, Kai Ning, Krstic, Aleksandar, Thorpe, Stephen D., del Río Hernández, Armando E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154384/ https://www.ncbi.nlm.nih.gov/pubmed/37130839 http://dx.doi.org/10.1038/s41389-023-00467-1 |
Ejemplares similares
-
G Protein-Coupled Estrogen Receptor Regulates Actin Cytoskeleton Dynamics to Impair Cell Polarization
por: Lachowski, Dariusz, et al.
Publicado: (2020) -
Self-Assembling Polypeptide Hydrogels as a Platform to Recapitulate the Tumor Microenvironment
por: Lachowski, Dariusz, et al.
Publicado: (2021) -
GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
por: Cortes, Ernesto, et al.
Publicado: (2018) -
GPER Activation Inhibits Cancer Cell Mechanotransduction and Basement Membrane Invasion via RhoA
por: Rice, Alistair, et al.
Publicado: (2020) -
Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells
por: Lachowski, Dariusz, et al.
Publicado: (2017)