Methionine restriction constrains lipoylation and activates mitochondria for nitrogenic synthesis of amino acids

Methionine restriction (MR) provides metabolic benefits in many organisms. However, mechanisms underlying the MR-induced effect remain incompletely understood. Here, we show in the budding yeast S. cerevisiae that MR relays a signal of S-adenosylmethionine (SAM) deprivation to adapt bioenergetic mit...

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Detalles Bibliográficos
Autores principales: Fang, Wen, Jiang, Liu, Zhu, Yibing, Yang, Sen, Qiu, Hong, Cheng, Jiou, Liang, Qingxi, Tu, Zong-cai, Ye, Cunqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154411/
https://www.ncbi.nlm.nih.gov/pubmed/37130856
http://dx.doi.org/10.1038/s41467-023-38289-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154411/
https://www.ncbi.nlm.nih.gov/pubmed/37130856
http://dx.doi.org/10.1038/s41467-023-38289-9

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