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Curcumin-loaded graphene oxide quantum dots enhance otoprotective effects via blocking cuproptosis

Background: Cisplatin (CIS) is widely used to treat various cancers but can cause ototoxicity and sensory hair cell loss in the inner ear. Copper induces an excessive production of reactive oxygen species (ROS) in hair cells, leading to the development of various antioxidants. Methods and results: T...

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Detalles Bibliográficos
Autores principales: Hu, An, Zhang, Jian-Wei, Yang, Li-Yun, Qiao, Pei-Pei, Lu, Dan, Yu, Ya-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154464/
https://www.ncbi.nlm.nih.gov/pubmed/37152642
http://dx.doi.org/10.3389/fbioe.2023.1183197