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Overexpression of mitogen-activated protein kinase phosphatase-1 in endothelial cells reduces blood-brain barrier injury in a mouse model of ischemic stroke

Ischemic stroke can cause blood-brain barrier (BBB) injury, which worsens brain damage induced by stroke. Abnormal expression of tight junction proteins in endothelial cells (ECs) can increase intracellular space and BBB leakage. Selective inhibition of mitogen-activated protein kinase, the negative...

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Detalles Bibliográficos
Autores principales: Qin, Xiu-De, Yang, Tai-Qin, Zeng, Jing-Hui, Cai, Hao-Bin, Qi, Shao-Hua, Jiang, Jian-Jun, Cheng, Ying, Xu, Long-Sheng, Bu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154501/
https://www.ncbi.nlm.nih.gov/pubmed/36751800
http://dx.doi.org/10.4103/1673-5374.363836