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Protein quality control and aggregation in the endoplasmic reticulum: From basic to bedside

Endoplasmic reticulum (ER) is the largest membrane-bound compartment in all cells and functions as a key regulator in protein biosynthesis, lipid metabolism, and calcium balance. Mammalian endoplasmic reticulum has evolved with an orchestrated protein quality control system to handle defective prote...

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Detalles Bibliográficos
Autores principales: Chen, Guofang, Wei, Tingyi, Ju, Furong, Li, Haisen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154544/
https://www.ncbi.nlm.nih.gov/pubmed/37152279
http://dx.doi.org/10.3389/fcell.2023.1156152