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Xue-Jie-San restricts ferroptosis in Crohn’s disease via inhibiting FGL1/NF-κB/STAT3 positive feedback loop

Crohn’s disease (CD) is an incurable inflammatory bowel disease due to unclear etiology and pathogenesis. Accumulating evidences have shown the harmful role of ferroptosis in CD onset and development. Additionally, fibrinogen-like protein 1 (FGL1) has been verified to be a potential therapeutic targ...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Zhang, Zhaozheng, Du, Jun, Yang, Xiao, Wang, Xiaopeng, Wen, Ke, Sun, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154545/
https://www.ncbi.nlm.nih.gov/pubmed/37153794
http://dx.doi.org/10.3389/fphar.2023.1148770