Syngeneic mouse model of human HER2+ metastatic breast cancer for the evaluation of trastuzumab emtansine combined with oncolytic rhabdovirus

BACKGROUND: Established mouse models of HER2+ cancer are based on the over-expression of rodent Neu/Erbb2 homologues, which are incompatible with human HER2 (huHER2) targeted therapeutics. Additionally, the use of immune-deficient xenograft or transgenic models precludes assessment of native anti-tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Taha, Zaid, Crupi, Mathieu J.F., Alluqmani, Nouf, Fareez, Faiha, Ng, Kristy, Sobh, Judy, Lee, Emily, Chen, Andrew, Thomson, Max, Spinelli, Marcus M., Ilkow, Carolina S., Bell, John C., Arulanandam, Rozanne, Diallo, Jean-Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
https://www.ncbi.nlm.nih.gov/pubmed/37153626
http://dx.doi.org/10.3389/fimmu.2023.1181014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154558/
https://www.ncbi.nlm.nih.gov/pubmed/37153626
http://dx.doi.org/10.3389/fimmu.2023.1181014

Ejemplares similares