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Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice

BACKGROUND: Recent in vitro studies strongly implicated mast cell-derived proteases as regulators of IL-33 activity by enzymatic cleavage in its central domain. A better understanding of the role of mast cell proteases on IL-33 activity in vivo is needed. We aimed to compare the expression of mast c...

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Detalles Bibliográficos
Autores principales: Krysko, Olga, Korsakova, Darya, Teufelberger, Andrea, De Meyer, Amse, Steels, Jill, De Ruyck, Natalie, van Ovost, Judith, Van Nevel, Sharon, Holtappels, Gabriele, Coppieters, Frauke, Ivanchenko, Mikhail, Braun, Harald, Vedunova, Maria, Krysko, Dmitri V., Bachert, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154570/
https://www.ncbi.nlm.nih.gov/pubmed/37153601
http://dx.doi.org/10.3389/fimmu.2023.1040493