Diazoxide is a powerful cardioprotectant but is not feasible in a realistic infarct scenario

INTRODUCTION: Diazoxide is a powerful cardioprotective agent that activates mitochondrial ATP-dependent K-channels and stimulates mitochondrial respiration. Diazoxide reduced infarct size in isolated rodent heart preparations and upon pretreatment in juvenile pigs with coronary occlusion/reperfusion...

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Detalles Bibliográficos
Autores principales: Kleinbongard, Petra, Lieder, Helmut, Skyschally, Andreas, Heusch, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154575/
https://www.ncbi.nlm.nih.gov/pubmed/37153458
http://dx.doi.org/10.3389/fcvm.2023.1173462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154575/
https://www.ncbi.nlm.nih.gov/pubmed/37153458
http://dx.doi.org/10.3389/fcvm.2023.1173462

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