Pre-pandemic SARS-CoV-2-specific IFN-γ and antibody responses were low in Ugandan samples and significantly reduced in HIV-positive specimens

INTRODUCTION: We investigated whether prior SARS-CoV-2-specific IFN-γ and antibody responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low disease severity. METHODS: We used nucleoprotein (N), spike (S), NTD, RBD, envelope, membrane, SD1/2-directed IFN-γ ELISpots,...

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Detalles Bibliográficos
Autores principales: Nantambi, Hellen, Sembera, Jackson, Ankunda, Violet, Ssali, Ivan, Kalyebi, Arthur Watelo, Oluka, Gerald Kevin, Kato, Laban, Ubaldo, Bahemuka, Kibengo, Freddie, Katende, Joseph Ssebwana, Gombe, Ben, Baine, Claire, Odoch, Geoffrey, Mugaba, Susan, Sande, Obondo James, Kaleebu, Pontiano, Serwanga, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154590/
https://www.ncbi.nlm.nih.gov/pubmed/37153598
http://dx.doi.org/10.3389/fimmu.2023.1148877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154590/
https://www.ncbi.nlm.nih.gov/pubmed/37153598
http://dx.doi.org/10.3389/fimmu.2023.1148877

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