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Pre-pandemic SARS-CoV-2-specific IFN-γ and antibody responses were low in Ugandan samples and significantly reduced in HIV-positive specimens
INTRODUCTION: We investigated whether prior SARS-CoV-2-specific IFN-γ and antibody responses in Ugandan COVID-19 pre-pandemic specimens aligned to this population's low disease severity. METHODS: We used nucleoprotein (N), spike (S), NTD, RBD, envelope, membrane, SD1/2-directed IFN-γ ELISpots,...
Autores principales: | Nantambi, Hellen, Sembera, Jackson, Ankunda, Violet, Ssali, Ivan, Kalyebi, Arthur Watelo, Oluka, Gerald Kevin, Kato, Laban, Ubaldo, Bahemuka, Kibengo, Freddie, Katende, Joseph Ssebwana, Gombe, Ben, Baine, Claire, Odoch, Geoffrey, Mugaba, Susan, Sande, Obondo James, Kaleebu, Pontiano, Serwanga, Jennifer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154590/ https://www.ncbi.nlm.nih.gov/pubmed/37153598 http://dx.doi.org/10.3389/fimmu.2023.1148877 |
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