A phase I study to assess safety, pharmacokinetics, and pharmacodynamics of a vaginal insert containing tenofovir alafenamide and elvitegravir

BACKGROUND: New multi-purpose prevention technology (MPT) products are needed to prevent human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV2). In this study, we evaluated a fast-dissolve insert that may be used vaginally or rectally for prevention of infection. OBJECTIVE: To des...

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Detalles Bibliográficos
Autores principales: Thurman, Andrea R., Ouattara, Louise A., Yousefieh, Nazita, Anderson, Peter L., Bushman, Lane R., Fang, Xi, Hanif, Homaira, Clark, Meredith, Singh, Onkar, Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154607/
https://www.ncbi.nlm.nih.gov/pubmed/37153145
http://dx.doi.org/10.3389/fcimb.2023.1130101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154607/
https://www.ncbi.nlm.nih.gov/pubmed/37153145
http://dx.doi.org/10.3389/fcimb.2023.1130101

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