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Overexpression of IGF2 affects mouse weight and glycolipid metabolism and IGF2 is positively related to macrosomia

OBJECTIVE: To investigate the effects of insulin-like growth factor 2 (IGF2) on growth and glycolipid metabolism, as well as the underlying mechanism. METHODS: A mouse model of IGF2 overexpression was constructed to measure weight gain before adulthood, to obtain the values of adult glycolipid metab...

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Detalles Bibliográficos
Autores principales: Zhang, Qidi, Qin, Shengtang, Huai, Jing, Yang, Huixia, Wei, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154688/
https://www.ncbi.nlm.nih.gov/pubmed/37152930
http://dx.doi.org/10.3389/fendo.2023.1030453