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Transcriptional re-programming of insulin B-chain epitope-specific T-follicular helper cells into anti-diabetogenic T-regulatory type-1 cells

Systemic delivery of nanoparticles (NPs) coated with mono-specific autoimmune disease-relevant peptide-major histocompatibility complex class II (pMHCII) molecules can resolve organ inflammation in various disease models in a disease-specific manner without impairing normal immunity. These compounds...

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Detalles Bibliográficos
Autores principales: Solé, Patricia, Parras, Daniel, Yamanouchi, Jun, Garnica, Josep, Garabatos, Nahir, Moro, Joel, Montaño, Javier, Mondal, Debajyoti, Fandos, César, Yang, Yang, Serra, Pau, Santamaria, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154693/
https://www.ncbi.nlm.nih.gov/pubmed/37153608
http://dx.doi.org/10.3389/fimmu.2023.1177722