Crizotinib‐based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradation

As one of the common malignant cancer types, gastric cancer (GC) is known for late‐stage diagnosis and poor prognosis. Overexpression of the receptor tyrosine kinase MET is associated with poor prognosis among patients with advanced stage GC. However, no MET inhibitor has been used for GC treatment....

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jin‐Jiao, Jin, Jin‐Mei, Gu, Wen‐Jie, Zhao, Zeng, Yuan, Hu, Zhou, Yu‐Dong, Nagle, Dale G., Xi, Qiu‐Lei, Zhang, Xue‐Mei, Sun, Qing‐Yan, Wu, Ye, Zhang, Wei‐Dong, Luan, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154821/
https://www.ncbi.nlm.nih.gov/pubmed/36692137
http://dx.doi.org/10.1111/cas.15733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154821/
https://www.ncbi.nlm.nih.gov/pubmed/36692137
http://dx.doi.org/10.1111/cas.15733

Ejemplares similares