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Crizotinib‐based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradation
As one of the common malignant cancer types, gastric cancer (GC) is known for late‐stage diagnosis and poor prognosis. Overexpression of the receptor tyrosine kinase MET is associated with poor prognosis among patients with advanced stage GC. However, no MET inhibitor has been used for GC treatment....
Autores principales: | Chen, Jin‐Jiao, Jin, Jin‐Mei, Gu, Wen‐Jie, Zhao, Zeng, Yuan, Hu, Zhou, Yu‐Dong, Nagle, Dale G., Xi, Qiu‐Lei, Zhang, Xue‐Mei, Sun, Qing‐Yan, Wu, Ye, Zhang, Wei‐Dong, Luan, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154821/ https://www.ncbi.nlm.nih.gov/pubmed/36692137 http://dx.doi.org/10.1111/cas.15733 |
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