Development of an osteosarcoma model with MYCN amplification and TP53 mutation in hiPS cell‐derived neural crest cells

Mesenchymal stem cell‐ or osteoblast‐derived osteosarcoma is the most common malignant bone tumor. Its highly metastatic malignant phenotypes, which are often associated with a poor prognosis, have been correlated with the modulation of TP53‐ and cell‐cycle‐related pathways. MYC, which regulates the...

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Detalles Bibliográficos
Autores principales: Mukae, Kyosuke, Takenobu, Hisanori, Endo, Yuki, Haruta, Masayuki, Shi, Tianyuan, Satoh, Shunpei, Ohira, Miki, Funato, Michinori, Toguchida, Junya, Osafune, Kenji, Nakahata, Tatsutoshi, Kanda, Hiroaki, Kamijo, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154822/
https://www.ncbi.nlm.nih.gov/pubmed/36661413
http://dx.doi.org/10.1111/cas.15730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154822/
https://www.ncbi.nlm.nih.gov/pubmed/36661413
http://dx.doi.org/10.1111/cas.15730

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