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Let‐7b‐5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1

Naked cuticle homolog 1 (NKD1), which is expressed at low levels in many tumors, is considered an inhibitor of the Wnt/β‐catenin pathway, but it is highly expressed in colon cancer and can promote colon cancer cell proliferation. miRNAs are involved in the occurrence and progression of many tumors....

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Detalles Bibliográficos
Autores principales: Dai, Yuyang, Liu, Jinsong, Li, Xuyan, Deng, Jianzhong, Zeng, Cheng, Lu, Wenbin, Hou, Yongzhong, Sheng, Ying, Wu, Honglin, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10154867/
https://www.ncbi.nlm.nih.gov/pubmed/36445120
http://dx.doi.org/10.1111/cas.15678