Reverse Translation Identifies the Synergistic Role of Immune Checkpoint Blockade and IL15 to Enhance Immunotherapy of Ovarian Cancer

Immune checkpoint blockade (ICB) has changed the standard of care for many patients with cancer, yet no ICB is approved for ovarian cancer. We hypothesized that maintenance therapy with an IL15 “superagonist” (N-803) and ICB in combination could induce potent immune activation in ovarian cancer. Usi...

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Detalles Bibliográficos
Autores principales: Felices, Martin, Wesley, Erin, Bendzick, Laura E., Kodal, Behiye, Hopps, Rachel, Grzywacz, Bartosz, Hinderlie, Peter, Miller, Jeffrey S., Geller, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155036/
https://www.ncbi.nlm.nih.gov/pubmed/36807510
http://dx.doi.org/10.1158/2326-6066.CIR-22-0600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155036/
https://www.ncbi.nlm.nih.gov/pubmed/36807510
http://dx.doi.org/10.1158/2326-6066.CIR-22-0600

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