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Low TCR Binding Strength Results in Increased Progenitor-like CD8(+) Tumor-Infiltrating Lymphocytes
T-cell receptor (TCR) binding strength to peptide-MHC antigen complex influences numerous T-cell functions. However, the vast diversity of a polyclonal T-cell repertoire for even a single antigen greatly increases the complexity of studying the impact of TCR affinity on T-cell function. Here, we det...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for Cancer Research
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155039/ https://www.ncbi.nlm.nih.gov/pubmed/36787375 http://dx.doi.org/10.1158/2326-6066.CIR-22-0761 |