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Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma

The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a lethal primary brain cancer for which there are no cur...

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Detalles Bibliográficos
Autores principales: Yeo, Alan T., Shah, Rushil, Aliazis, Konstantinos, Pal, Rinku, Xu, Tuoye, Zhang, Piyan, Rawal, Shruti, Rose, Christopher M., Varn, Frederick S., Appleman, Vicky A., Yoon, Joon, Varma, Hemant, Gygi, Steven P., Verhaak, Roel G.W., Boussiotis, Vassiliki A., Charest, Al
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155040/
https://www.ncbi.nlm.nih.gov/pubmed/36881002
http://dx.doi.org/10.1158/2326-6066.CIR-22-0655