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Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients’ response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood. Glioblastoma (GBM) is a lethal primary brain cancer for which there are no cur...
Autores principales: | Yeo, Alan T., Shah, Rushil, Aliazis, Konstantinos, Pal, Rinku, Xu, Tuoye, Zhang, Piyan, Rawal, Shruti, Rose, Christopher M., Varn, Frederick S., Appleman, Vicky A., Yoon, Joon, Varma, Hemant, Gygi, Steven P., Verhaak, Roel G.W., Boussiotis, Vassiliki A., Charest, Al |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155040/ https://www.ncbi.nlm.nih.gov/pubmed/36881002 http://dx.doi.org/10.1158/2326-6066.CIR-22-0655 |
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