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Furin as a therapeutic target in cystic fibrosis airways disease

Clinical management of cystic fibrosis (CF) has been greatly improved by the development of small molecule modulators of the CF transmembrane conductance regulator (CFTR). These drugs help to address some of the basic genetic defects of CFTR; however, no suitable CFTR modulators exist for 10% of peo...

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Detalles Bibliográficos
Autores principales: Douglas, Lisa E.J., Reihill, James A., Montgomery, Bethany M., Martin, S. Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155048/
https://www.ncbi.nlm.nih.gov/pubmed/37137509
http://dx.doi.org/10.1183/16000617.0256-2022