Assessment of Tumor Mutational Burden and Outcomes in Patients With Diverse Advanced Cancers Treated With Immunotherapy

IMPORTANCE: There are few studies assessing the association of tumor mutational burden (TMB) and clinical outcomes in a large cohort of patients with diverse advanced cancers. OBJECTIVE: To clinically validate a TMB biomarker from a next-generation sequencing targeted gene panel assay. DESIGN, SETTI...

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Detalles Bibliográficos
Autores principales: Aggarwal, Charu, Ben-Shachar, Rotem, Gao, Yinjie, Hyun, Seung Won, Rivers, Zachary, Epstein, Carrie, Kaneva, Kristiyana, Sangli, Chithra, Nimeiri, Halla, Patel, Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155064/
https://www.ncbi.nlm.nih.gov/pubmed/37129893
http://dx.doi.org/10.1001/jamanetworkopen.2023.11181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155064/
https://www.ncbi.nlm.nih.gov/pubmed/37129893
http://dx.doi.org/10.1001/jamanetworkopen.2023.11181

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