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Competitive Adsorption of a Monoclonal Antibody and Nonionic Surfactant at the PDMS/Water Interface

[Image: see text] Interfacial adsorption of monoclonal antibodies (mAbs) can cause structural deformation and induce undesired aggregation and precipitation. Nonionic surfactants are often added to reduce interfacial adsorption of mAbs which may occur during manufacturing, storage, and/or administra...

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Detalles Bibliográficos
Autores principales: Shen, Kangcheng, Hu, Xuzhi, Li, Zongyi, Liao, Mingrui, Zhuang, Zeyuan, Ruane, Sean, Wang, Ziwei, Li, Peixun, Micciulla, Samantha, Kasinathan, Narayanan, Kalonia, Cavan, Lu, Jian Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155179/
https://www.ncbi.nlm.nih.gov/pubmed/37012645
http://dx.doi.org/10.1021/acs.molpharmaceut.2c01099