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Competitive Adsorption of a Monoclonal Antibody and Nonionic Surfactant at the PDMS/Water Interface
[Image: see text] Interfacial adsorption of monoclonal antibodies (mAbs) can cause structural deformation and induce undesired aggregation and precipitation. Nonionic surfactants are often added to reduce interfacial adsorption of mAbs which may occur during manufacturing, storage, and/or administra...
Autores principales: | Shen, Kangcheng, Hu, Xuzhi, Li, Zongyi, Liao, Mingrui, Zhuang, Zeyuan, Ruane, Sean, Wang, Ziwei, Li, Peixun, Micciulla, Samantha, Kasinathan, Narayanan, Kalonia, Cavan, Lu, Jian Ren |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155179/ https://www.ncbi.nlm.nih.gov/pubmed/37012645 http://dx.doi.org/10.1021/acs.molpharmaceut.2c01099 |
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