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Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM- and miR-152-3p/CaMKIIα-mediated inflammatory and apoptotic pathways

INTRODUCTION: Although vascular dementia (VaD) is the second most prevalent form of dementia, there is currently a lack of effective treatments. Tilianin, isolated from the traditional drug Dracocephalum moldavica L., may protect against ischemic injury by inhibiting oxidative stress and inflammatio...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Tan, Linjie, Liu, Mimin, Zeng, Li, Zhao, Kaiyue, Cai, Zhongdi, Sun, Shengnan, Li, Zhuorong, Liu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155197/
https://www.ncbi.nlm.nih.gov/pubmed/37153565
http://dx.doi.org/10.3389/fimmu.2023.1118808