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Tilianin improves cognition in a vascular dementia rodent model by targeting miR-193b-3p/CaM- and miR-152-3p/CaMKIIα-mediated inflammatory and apoptotic pathways
INTRODUCTION: Although vascular dementia (VaD) is the second most prevalent form of dementia, there is currently a lack of effective treatments. Tilianin, isolated from the traditional drug Dracocephalum moldavica L., may protect against ischemic injury by inhibiting oxidative stress and inflammatio...
Autores principales: | Sun, Ting, Tan, Linjie, Liu, Mimin, Zeng, Li, Zhao, Kaiyue, Cai, Zhongdi, Sun, Shengnan, Li, Zhuorong, Liu, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155197/ https://www.ncbi.nlm.nih.gov/pubmed/37153565 http://dx.doi.org/10.3389/fimmu.2023.1118808 |
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