Human Antibody V(H) Domains Targeting GPNMB and VCAM-1 as Candidate Therapeutics for Cancers

[Image: see text] The elevated expression of GPNMB and VCAM-1 has been observed in many cancers including breast cancer, melanoma, and prostate cancers. Such overexpression of GPNMB and VCAM-1 has been associated with poor prognosis and increased cancer metastasis. Thus, GPNMB and VCAM-1 are potenti...

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Detalles Bibliográficos
Autores principales: Chu, Xiaojie, Li, Wei, Hines, Margaret G., Lyakhov, Ilya, Mellors, John W., Dimitrov, Dimiter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155206/
https://www.ncbi.nlm.nih.gov/pubmed/37067377
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155206/
https://www.ncbi.nlm.nih.gov/pubmed/37067377
http://dx.doi.org/10.1021/acs.molpharmaceut.3c00173

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