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Human Antibody V(H) Domains Targeting GPNMB and VCAM-1 as Candidate Therapeutics for Cancers
[Image: see text] The elevated expression of GPNMB and VCAM-1 has been observed in many cancers including breast cancer, melanoma, and prostate cancers. Such overexpression of GPNMB and VCAM-1 has been associated with poor prognosis and increased cancer metastasis. Thus, GPNMB and VCAM-1 are potenti...
Autores principales: | Chu, Xiaojie, Li, Wei, Hines, Margaret G., Lyakhov, Ilya, Mellors, John W., Dimitrov, Dimiter S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155206/ https://www.ncbi.nlm.nih.gov/pubmed/37067377 http://dx.doi.org/10.1021/acs.molpharmaceut.3c00173 |
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