Loss of Ufl1/Ufbp1 in hepatocytes promotes liver pathological damage and carcinogenesis through activating mTOR signaling

BACKGROUND: Ufm1-specific ligase 1 (Ufl1) and Ufm1-binding protein 1 (Ufbp1), as putative targets of ubiquitin-fold modifier 1 (Ufm1), have been implicated in several pathogenesis-related signaling pathways. However, little is known about their functional roles in liver disease. METHODS: Hepatocyte-...

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Detalles Bibliográficos
Autores principales: Chen, Fanghui, Sheng, Le, Zhou, Tianci, Yan, Li, Loveless, Reid, Li, Honglin, Teng, Yong, Cai, Yafei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155312/
https://www.ncbi.nlm.nih.gov/pubmed/37131258
http://dx.doi.org/10.1186/s13046-023-02681-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155312/
https://www.ncbi.nlm.nih.gov/pubmed/37131258
http://dx.doi.org/10.1186/s13046-023-02681-6

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