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Melatonin and erastin emerge synergistic anti-tumor effects on oral squamous cell carcinoma by inducing apoptosis, ferroptosis, and inhibiting autophagy through promoting ROS

BACKGROUND: Oral squamous cell carcinomas are one of the most common cancers worldwide with aggressive behavior and poor prognosis. Reactive oxygen species (ROS) are associated with cancer and cause various types of regulated cell death (RCD). Inducing the RCD pathway by modulating ROS levels is imp...

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Detalles Bibliográficos
Autores principales: Wang, Leilei, Wang, Chuan, Li, Xuan, Tao, Zhuoying, Zhu, Wangyong, Su, Yuxiong, Choi, Wing Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155313/
https://www.ncbi.nlm.nih.gov/pubmed/37131152
http://dx.doi.org/10.1186/s11658-023-00449-6