P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas

Molecular characterization of gliomas has uncovered genomic signatures with significant impact on tumor diagnosis and prognostication. CDKN2A is a tumor suppressor gene involved in cell cycle control. Homozygous deletion of the CDKN2A/B locus has been implicated in both gliomagenesis and tumor progr...

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Detalles Bibliográficos
Autores principales: Vij, Meenakshi, Cho, Benjamin B., Yokoda, Raquel T., Rashidipour, Omid, Umphlett, Melissa, Richardson, Timothy E., Tsankova, Nadejda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155323/
https://www.ncbi.nlm.nih.gov/pubmed/37138345
http://dx.doi.org/10.1186/s40478-023-01573-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155323/
https://www.ncbi.nlm.nih.gov/pubmed/37138345
http://dx.doi.org/10.1186/s40478-023-01573-2

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