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Biosensor-guided rapid screening for improved recombinant protein secretion in Pichia pastoris
Pichia pastoris (Komagataella phaffii) is widely used for industrial production of heterologous proteins due to high secretory capabilities but selection of highly productive engineered strains remains a limiting step. Despite availability of a comprehensive molecular toolbox for construct design an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155391/ https://www.ncbi.nlm.nih.gov/pubmed/37138331 http://dx.doi.org/10.1186/s12934-023-02089-z |