Epigenetic priming improves salvage chemotherapy in diffuse large B-cell lymphoma via endogenous retrovirus-induced cGAS-STING activation

BACKGROUND: Although most patients with diffuse large B-cell lymphoma (DLBCL) achieve complete remission after first-line rituximab-containing immunochemotherapy, up to 40% of patients relapse and require salvage therapy. Among those patients, a substantial proportion remain refractory to salvage th...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Min, Suji, Kim, Dongchan, Park, Jihyun, Park, Eunchae, Koh, Youngil, Shin, Dong-Yeop, Kim, Tae Kon, Byun, Ja Min, Yoon, Sung-Soo, Hong, Junshik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155448/
https://www.ncbi.nlm.nih.gov/pubmed/37138342
http://dx.doi.org/10.1186/s13148-023-01493-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10155448/
https://www.ncbi.nlm.nih.gov/pubmed/37138342
http://dx.doi.org/10.1186/s13148-023-01493-x

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